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Microcephaly / Micrencephaly by G. Lyon |
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mardi, 25 avril 2006 |
Clinical Facts.
 Ending a long debate on the mechanism of head growth, the French scientist Geoffroy Saint-Hilaire, speaking at the October 1820 meeting of the Academie des Sciences in Paris, asserted that the development of the skull was determined by and proportional to the volume of the brain...
This seems now an evidence: the size of the brain is estimated by measuring the head cicumference .
However the size of the skull and that of the brain may differ significantly.
In some instances of severe prenatal infectious or developmental disorders of the
central nervoud system there is a considerable discrepancy , in the neonate or young infant, between a very small cerebral mass and a normal or slighly reduced head circumference .
Possibly ,the pressure exerted on the skull by the accumulation of pericerebral CSF explains this situation.
Not sufficient attention is given to this this relatively common phenomenon in Pediatric Textbooks.
(I have seen a number of such cases ,some of which with Pr Ph. Evrard. Pr. Leroy describes this phenomenon in a recent work ,to be published.
Pr. Gilles Lyon.
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Last Updated ( mercredi, 26 avril 2006 )
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Chroniques